Palisaded encapsulated neuroma: an uncommon tumour at uncommon location

PEN also known as ‘solitary circumscribed neuroma’ is an uncommon, sporadic, cutaneous, benign, intraneural tumor, which usually presents as asymptomatic, solitary or multiple, firm, rubbery, skin-coloured or pink, papule or nodule, commonly localized on the face or close to a muco-cutaneous junction in middle aged adults with equal sex preponderance [1]. It was first described by Reed et al in 1972 [1]. Being solitary or multiple, it has never been seen to be associated with neurofibromatosis or multiple endocrine neoplasia [2]. Clinically, it is more commonly misdiagnosed with schwannoma, neurofibroma and dermatofibroma so it is imperative to histopathological evaluation in all such cases.